Retrograde amnesia after electroconvulsive therapy: A temporary effect?

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Retrograde amnesia after electroconvulsive therapy: a temporary effect?

OBJECTIVE Although electroconvulsive therapy (ECT) is generally considered effective against depression, it remains controversial because of its association with retrograde memory loss. Here, we assessed memory after ECT in circumstances most likely to yield strong retrograde amnesia. METHOD A cohort of patients undergoing ECT for major depression was tested before and after ECT, and again at...

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BR-16A restricts development of electroconvulsive shock-induced retrograde amnesia.

Forty nine adult male Sprague Dawley rats were selected for rapid learning in a T-maze to study the effects of BR-16A, a herbal preparation on ECS-induced retrograde amnesia. Half the rats received 200 mg/kg BR-16A and the other half received vehicle alone. The rats were trained to run into the enclosed chamber of either the left or the right arm on a T-maze; a food pellet served as a reward in...

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Electroconvulsive Therapy in Severe Depression: Is Amnesia a Problem?

Introduction: Depression is the leading global cause of disability and approximately, 350 million people suffer from depression worldwide. Despite the availability of numerous psychopharmacological treatments, evidence indicates that only 60–70% of persons who tolerate antidepressants will respond to first-line drug therapy for major depressive disorder. Resistance to the antidepressant medicat...

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Retrograde Amnesia and the " Reminder Effect "

I D. H. Hubel and T. N. Wiesel, J. Physiol. (Lond.) 160, 106 (1962); J. Neutrophysiol. 28, 229 (1965). 2. , J. Physiol. (Lond.) 195, 215 (1968). 3. J. D. Pettigrew, T. Nikara, P. 0. Bishop, Exp. Brain Res. 6, 373 (1968). 4. F. W. Campbell, B. G. Cleland, G. F. Cooper, C. Enroth-Cugell, J. Physiol. (Lond.) 198, 237 (1968). 5. For review of evidence, see G. F. Poggio, in Handbook of Medical Physi...

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Retrograde amnesia.

In humans, the phenomenon of temporally graded retrograde amnesia has been described in the clinic and the laboratory for more than 100 years. In the 1990s, retrograde amnesia began to be studied prospectively in experimental animals. We identified 13 published studies in which animals were given equivalent training at two or more separate times before damage to the fornix or hippocampal format...

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ژورنال

عنوان ژورنال: Journal of Affective Disorders

سال: 2011

ISSN: 0165-0327

DOI: 10.1016/j.jad.2011.02.026